lateral_ventricle_tumor

Lateral ventricle tumor

Lateral ventricle tumors are rare and account for 50% of all intraventricular tumors in adults and 25% in children.

For the radiological analyses, the lateral ventricle tumors are classified into two groups, as follows: 1. Intraventricular tumors arise in the projection of the choroid plexus, the tela chorioidea and the ependyma and grow in the lateral ventricle. 2. Paraventricular tumors arise from the wall of the neuroglia that not only bulges into the ventricle but in addition infiltrates the substance of the surrounding brain. Following conclusions are obtained. (1) Unilateral hydrocephalus, which is shown clearly by vascular displacements in subependymal veins, is demonstrated in both tumor groups. (2) There are different findings on the feeding arteries, the draining veins, and the tumor stains between the two tumor groups. (3) In the intraventricular tumor groups, the anterior choroidal artery supplying the tumor is its plex segments and atrial segments. (4) On the other hand, in the paraventricular tumors group, the anterior choroidal artery supplying the tumor is its superior penetrating branch to the cerebral parenchyma. (5) Cerebral angiograms can reveal definite signs of the intraventricular mass, but it is sometimes difficult to evaluate whether its space-occupying lesions infiltrate the cerebral substance below the wall of the lateral ventricle, or not. (6) CT scan is a useful neuroradiological method in the differential diagnosis between two tumor groups, and a CT scan provides an anatomical diagnosis rather than a histological one. (7) The accurate diagnosis of the tumors of the lateral ventricle can be demonstrated by both cerebral angiograms and CT scan 1).


Lateral ventricle tumors including the trigone are divided into true intraventricular and paraventricular tumors according to the Koos and Laubichler classification 2).

The former include meningiomas, ependymomas, colloid cysts, metastatic tumors, astrocytomas, oligodendrogliomas, or glioblastomas.

Choroid plexus papillomas (CPP) are uncommon benign brain tumors that usually arise in the fourth ventricle in adults and lateral ventricles in children.

Lateral ventricle epidermoid

A total of 72 patients underwent surgery for lateral ventricle tumors. The mean patient age was 39 years (range, 6 mo to 78 yr). Raised intracranial pressure occurred in 53% of patients, followed by mental disturbances or psychiatric symptoms (32%) and motor deficits (21%). The transcortical approach was used in 44 patients, and an interhemispheric approach was used in 28 patients; a transcallosal approach was used in 16 patients, and a para splenial approach was used in 12 patients. Neuropsychological tests were performed in selected patients.

Total resection was performed in 82% of patients. Sixty-five percent of tumors were benign and low-grade tumors. There was no surgical mortality, and the morbidity rate was 11%. Postoperative epilepsy (5.9%) was significantly increased in the transcortical group. The mean follow-up period was 55 months; 59% of patients achieved good recovery and moderate disability. In postoperative neuropsychological testing sessions, deficits in verbal memory were observed in six patients (8%). Final morbidity correlated well with the preoperative clinical condition and pathological diagnosis.

Lateral ventricle tumors can be treated best by careful selection of the approach according to tumor origin and development. Overall, the transcallosal approach is preferred, but in patients with transependymal growth or large primary or secondary ventricular tumors, the transcortical is a better option 3).


1)
Kitaoka K, Tashiro K, Sato M, Abe H, Tsuru M, Miyasaka K. [Lateral ventricle tumors. (Part 2) -Neuroradiological analyses of 30 cases- (author's transl)]. No Shinkei Geka. 1978 Dec;6(12):1181-92. Japanese. PubMed PMID: 732935.
2)
Koos W, Laubichler W. [Brain Tumors with Reference to the ventricular system] Nervenarzt. 1964;35:333–343
3)
D'Angelo VA, Galarza M, Catapano D, Monte V, Bisceglia M, Carosi I. Lateral ventricle tumors: surgical strategies according to tumor origin and development–a series of 72 cases. Neurosurgery. 2008 Jun;62(6 Suppl 3):1066-75. doi: 10.1227/01.neu.0000333772.35822.37. PubMed PMID: 18695527.
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