recurrent_lumbar_disc_herniation_risk_factors

Recurrent Lumbar Disc Herniation Risk Factors


Multiple risk factors including smoking, diabetes mellitus, obesity, intraoperative technique, and biomechanical factors may contribute to the development of recurrent disc disease 1).


In a study of 2021, risk factors for early recurrent lumbar disc herniation after lumbar discectomy were age ≥ 50 years and moderate disc degeneration. The annular closure device reduced the risk of early reherniation 2).


A study in 2017 suggested that patients who had recurrent lumbar disc herniation had preoperative higher disc height and higher body mass index. Modic endplate changes had a higher tendency for recurrence of lumbar disc herniation. Well-planned and well-conducted large-scale prospective cohort studies are needed to confirm this and enable convenient treatment modalities to prevent recurrent disc pathology 3).

A subligamentous disc herniation and patient's age inferior to 35 years at the time of the first surgery are risk factors for requiring surgical treatment of a first RLDH among workers' compensation patients 4).

Young adults (< 40 years) with uncorrected scoliosis are at higher risk of recurrent lumbar disc herniation (LDH) after lumbar microdiscectomy 5).

Patients in the Fragment-Fissure group, who had disc fragments and a small anular defect, had the best overall outcomes and the lowest rates of reherniation (1%) and reoperation (1%). Patients in the Fragment-Contained group had a 10% rate of reherniation and a 5% rate of reoperation. Patients in the Fragment-Defect group, who had extruded fragments and massive posterior anular loss, had a 27% rate of reherniation and a 21% rate of reoperation. Patients in the No Fragment-Contained group did poorly: 38% had recurrent or persistent sciatica, and the standard outcomes scores were less improved compared with those in the other groups (p < 0.001).

Intraoperative findings, as described, were more clearly associated with outcomes than were demographic, socioeconomic, or clinical variables. The degree of anular competence after discectomy and the type of herniation appear to have value for the prediction of the recurrence of sciatica, reoperation, and clinical outcome following lumbar discectomy 6).

Current smoker was an independent risk factor for sRDH reoperation. These findings are important for spinal surgeons and rehabilitation specialists in risk assessment, consenting patients, and perioperative management 7).


1)
Shepard N, Cho W. Recurrent Lumbar Disc Herniation: A Review. Global Spine J. 2019 Apr;9(2):202-209. doi: 10.1177/2192568217745063. Epub 2017 Dec 18. Review. PubMed PMID: 30984501; PubMed Central PMCID: PMC6448208.
2)
Kienzler JC, Fandino J, Van de Kelft E, Eustacchio S, Bouma GJ; Barricaid® Annular Closure RCT Study Group. Risk factors for early reherniation after lumbar discectomy with or without annular closure: results of a multicenter randomized controlled study. Acta Neurochir (Wien). 2021 Jan;163(1):259-268. doi: 10.1007/s00701-020-04505-4. Epub 2020 Oct 21. PMID: 33085021.
3)
Yaman ME, Kazancı A, Yaman ND, Baş F, Ayberk G. Factors that influence recurrent lumbar disc herniation. Hong Kong Med J. 2017 Jun;23(3):258-63. doi: 10.12809/hkmj164852. Epub 2017 Mar 3. PubMed PMID: 28253483.
4)
Yurac R, Zamorano JJ, Lira F, Valiente D, Ballesteros V, Urzúa A. Risk factors for the need of surgical treatment of a first recurrent lumbar disc herniation. Eur Spine J. 2015 Oct 15. [Epub ahead of print] PubMed PMID: 26471389.
5)
Chang HK, Chang HC, Wu JC, Tu TH, Fay LY, Chang PY, Wu CL, Huang WC, Cheng H. Scoliosis may increase the risk of recurrence of lumbar disc herniation after microdiscectomy. J Neurosurg Spine. 2016 Apr;24(4):586-91. doi: 10.3171/2015.7.SPINE15133. Epub 2015 Dec 11. PubMed PMID: 26654337.
6)
Carragee EJ, Han MY, Suen PW, et al: Clinical outcomes after lumbar discectomy for sciatica: the effects of fragment type and anular competence. J Bone Joint Surg Am 85:102–108, 2003
7)
Geere JH, Swamy GN, Hunter PR, Geere JL, Lutchman LN, Cook AJ, Rai AS. Incidence and risk factors for five-year recurrent disc herniation after primary single-level lumbar discectomy. Bone Joint J. 2023 Mar 1;105-B(3):315-322. doi: 10.1302/0301-620X.105B3.BJJ-2022-1005.R2. PMID: 36854329.
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