Intracranial metastases classification
can be classified based on various factors, including the number and location of the metastatic lesions, as well as the primary site of the cancer. Here's a general classification scheme:
Number of Lesions
Solitary Metastasis: Refers to a single metastatic lesion in the brain.
Multiple Metastases: Refers to the presence of two or more metastatic lesions in the brain.
Location of Metastases
Supratentorial Metastases: Metastases located above the tentorium cerebelli, including the cerebral hemispheres.
Infratentorial Metastases: Metastases located below the tentorium cerebelli, including the cerebellum and brainstem.
Cortical, Subcortical, or Deep Brain Metastases: Depending on the depth within the brain where the metastases occur.
Leptomeningeal Metastases: Metastases involving the meninges, the membranes covering the brain and spinal cord.
Primary Site of Cancer
Breast Cancer Metastases: Metastases originating from breast cancer.
Lung Cancer Metastases: Metastases originating from lung cancer.
Renal Cell Carcinoma Metastases: Metastases originating from renal cell carcinoma.
Melanoma Metastases: Metastases originating from melanoma, which can have a predilection for the brain.
Radiological Features
Hemorrhagic Metastases: Metastases with evidence of bleeding.
Cystic Metastases: Metastases with cystic components.
Ring-Enhancing Metastases: Metastases with a ring of enhancement on contrast-enhanced imaging, often seen in abscesses and some metastases.
Histological Features
Adenocarcinoma Metastases: Metastases originating from glandular tissue.
Squamous Cell Carcinoma Metastases: Metastases originating from squamous epithelial cells.
Small Cell Carcinoma Metastases: Metastases originating from neuroendocrine cells, often seen in lung cancer.
Classification systems may vary depending on the context and specialty, such as oncology, neurology, or radiology. The classification helps in guiding treatment decisions and predicting prognosis for patients with intracranial metastases.